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PDF] The Nedd8-activating enzyme inhibitor MLN4924 induces autophagy and  apoptosis to suppress liver cancer cell growth. | Semantic Scholar
PDF] The Nedd8-activating enzyme inhibitor MLN4924 induces autophagy and apoptosis to suppress liver cancer cell growth. | Semantic Scholar

Anticancer drug discovery by targeting cullin neddylation - ScienceDirect
Anticancer drug discovery by targeting cullin neddylation - ScienceDirect

Pevonedistat (MLN4924): mechanism of cell death induction and therapeutic  potential in colorectal cancer | Cell Death Discovery
Pevonedistat (MLN4924): mechanism of cell death induction and therapeutic potential in colorectal cancer | Cell Death Discovery

Model for redox regulation of ENaC where reactive ROS or MLN4924... |  Download Scientific Diagram
Model for redox regulation of ENaC where reactive ROS or MLN4924... | Download Scientific Diagram

Continued ) F, schematic illustration of proposed mechanism underlying... |  Download Scientific Diagram
Continued ) F, schematic illustration of proposed mechanism underlying... | Download Scientific Diagram

Blockage of neddylation modification stimulates tumor sphere formation in  vitro and stem cell differentiation and wound healing in vivo | PNAS
Blockage of neddylation modification stimulates tumor sphere formation in vitro and stem cell differentiation and wound healing in vivo | PNAS

Mechanism of MLN4924 action. Proposed mechanisms of how MLN4924... |  Download Scientific Diagram
Mechanism of MLN4924 action. Proposed mechanisms of how MLN4924... | Download Scientific Diagram

A model for the role of MLN4924 in mtOr signaling inactivation.... |  Download Scientific Diagram
A model for the role of MLN4924 in mtOr signaling inactivation.... | Download Scientific Diagram

IJMS | Free Full-Text | MLN4924, a Protein Neddylation Inhibitor,  Suppresses the Growth of Human Chondrosarcoma through Inhibiting Cell  Proliferation and Inducing Endoplasmic Reticulum Stress-Related Apoptosis
IJMS | Free Full-Text | MLN4924, a Protein Neddylation Inhibitor, Suppresses the Growth of Human Chondrosarcoma through Inhibiting Cell Proliferation and Inducing Endoplasmic Reticulum Stress-Related Apoptosis

SKP2 drives the sensitivity to neddylation inhibitors and cisplatin in  malignant pleural mesothelioma | Journal of Experimental & Clinical Cancer  Research | Full Text
SKP2 drives the sensitivity to neddylation inhibitors and cisplatin in malignant pleural mesothelioma | Journal of Experimental & Clinical Cancer Research | Full Text

Cardioprotective effect of MLN4924 on ameliorating autophagic flux  impairment in myocardial ischemia-reperfusion injury by Sirt1 -  ScienceDirect
Cardioprotective effect of MLN4924 on ameliorating autophagic flux impairment in myocardial ischemia-reperfusion injury by Sirt1 - ScienceDirect

The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury  in mice | PNAS
The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice | PNAS

Preclinical studies reveal MLN4924 is a promising new retinoblastoma  therapy | Cell Death Discovery
Preclinical studies reveal MLN4924 is a promising new retinoblastoma therapy | Cell Death Discovery

Neddylation of HER2 Inhibits its Protein Degradation and promotes Breast  Cancer Progression
Neddylation of HER2 Inhibits its Protein Degradation and promotes Breast Cancer Progression

Pevonedistat - an overview | ScienceDirect Topics
Pevonedistat - an overview | ScienceDirect Topics

Targeting Neddylation Pathways to Inactivate Cullin-RING Ligases for  Anticancer Therapy | Antioxidants & Redox Signaling
Targeting Neddylation Pathways to Inactivate Cullin-RING Ligases for Anticancer Therapy | Antioxidants & Redox Signaling

Frontiers | Advances in Cancer Treatment by Targeting the Neddylation  Pathway
Frontiers | Advances in Cancer Treatment by Targeting the Neddylation Pathway

Frontiers | Targeting Cullin-RING E3 Ligases for Radiosensitization: From  NEDDylation Inhibition to PROTACs
Frontiers | Targeting Cullin-RING E3 Ligases for Radiosensitization: From NEDDylation Inhibition to PROTACs

The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury  in mice | PNAS
The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice | PNAS

Neddylation Pathway as a Novel Anti-cancer Target: Mechanistic  Investigation and Therapeutic Implication | Bentham Science
Neddylation Pathway as a Novel Anti-cancer Target: Mechanistic Investigation and Therapeutic Implication | Bentham Science

Working model. Inhibition of neddylation pathway with MLN4924... | Download  Scientific Diagram
Working model. Inhibition of neddylation pathway with MLN4924... | Download Scientific Diagram

Inhibition of neddylation modification by MLN4924 sensitizes hepatocellular  carcinoma cells to sorafenib
Inhibition of neddylation modification by MLN4924 sensitizes hepatocellular carcinoma cells to sorafenib

MLN4924 specifically inhibits neddylation and suppresses the growth of... |  Download Scientific Diagram
MLN4924 specifically inhibits neddylation and suppresses the growth of... | Download Scientific Diagram