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PDF] The Nedd8-activating enzyme inhibitor MLN4924 induces autophagy and apoptosis to suppress liver cancer cell growth. | Semantic Scholar
Anticancer drug discovery by targeting cullin neddylation - ScienceDirect
Pevonedistat (MLN4924): mechanism of cell death induction and therapeutic potential in colorectal cancer | Cell Death Discovery
Model for redox regulation of ENaC where reactive ROS or MLN4924... | Download Scientific Diagram
Continued ) F, schematic illustration of proposed mechanism underlying... | Download Scientific Diagram
Blockage of neddylation modification stimulates tumor sphere formation in vitro and stem cell differentiation and wound healing in vivo | PNAS
Mechanism of MLN4924 action. Proposed mechanisms of how MLN4924... | Download Scientific Diagram
A model for the role of MLN4924 in mtOr signaling inactivation.... | Download Scientific Diagram
IJMS | Free Full-Text | MLN4924, a Protein Neddylation Inhibitor, Suppresses the Growth of Human Chondrosarcoma through Inhibiting Cell Proliferation and Inducing Endoplasmic Reticulum Stress-Related Apoptosis
SKP2 drives the sensitivity to neddylation inhibitors and cisplatin in malignant pleural mesothelioma | Journal of Experimental & Clinical Cancer Research | Full Text
Cardioprotective effect of MLN4924 on ameliorating autophagic flux impairment in myocardial ischemia-reperfusion injury by Sirt1 - ScienceDirect
The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice | PNAS
Preclinical studies reveal MLN4924 is a promising new retinoblastoma therapy | Cell Death Discovery
Neddylation of HER2 Inhibits its Protein Degradation and promotes Breast Cancer Progression
Pevonedistat - an overview | ScienceDirect Topics
Targeting Neddylation Pathways to Inactivate Cullin-RING Ligases for Anticancer Therapy | Antioxidants & Redox Signaling
Frontiers | Advances in Cancer Treatment by Targeting the Neddylation Pathway
Frontiers | Targeting Cullin-RING E3 Ligases for Radiosensitization: From NEDDylation Inhibition to PROTACs
The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice | PNAS
Neddylation Pathway as a Novel Anti-cancer Target: Mechanistic Investigation and Therapeutic Implication | Bentham Science
Working model. Inhibition of neddylation pathway with MLN4924... | Download Scientific Diagram
Inhibition of neddylation modification by MLN4924 sensitizes hepatocellular carcinoma cells to sorafenib
MLN4924 specifically inhibits neddylation and suppresses the growth of... | Download Scientific Diagram